期刊论文

Clinical effect of Chaishao Liujunzi decoction combined with Wubei San in treatment of refractory gastroesophageal reflux disease：an analysis of 96 cases

中文

湖南中医杂志

1003-7705

2017

33

6

10-12

10.16808/j.cnki.issn1003-7705.2017.06.004

2013年全国名老中医蒋士生传承工作室建设项目 全国第五批名老中医药专家学术继承项目 湖南省中医药科研计划项目（编号：201563）

本校为第一机构

目的：观察柴芍六君子汤合乌贝散治疗难治性胃食管反流病（GERD）的临床疗效。方法：将192例GERD患者随机分为2组,治疗组96例给予柴芍六君子汤合乌贝散治疗,对照组96例给予埃索美拉唑治疗。观察比较2组临床疗效及症状评分、RDQ积分与HADS积分。结果：总有效率治疗组为95.8%,对照组为62.5%,组间比较,差异有统计学意义（P〈0.01）;2组症状评分、RDQ积分、HADS积分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P〈0.05）。结论：柴芍六君子汤合乌贝散治疗难治性GERD疗效确切,可改善患者症状及焦虑、抑郁状态,提高患者生活质量。

Objective：To investigate the clinical effect of Chaishao Liujunzi decoction combined with Wubei San in the treatment of refractory gastroesophageal reflux disease （GERD）. Methods：A total of 192 patients with GERD were randomly divided into treatment group and control group, with 96 patients in each group. The patients in the treatment group were treated with Chaishao Liujunzi decoction combined with Wubei San, and those in the control group were given esomeprazole. The clinical outcome, symptom score, Reflux Diagnostic Questionnaire （RDQ）...