期刊论文

Effect of tea polyphenol on bacterial diversity in saliva of patients with fetid breath

中文

湖南中医杂志

1003-7705

2019

35

8

138-141

10.16808/j.cnki.issn1003-7705.2019.08.062

2017年度湖南省大学生研究性学习和创新性试验计划项目；

本校为第一机构

目的:评价茶多酚在口臭患者口腔微生态中的作用,通过分析样本内细菌群落结构差异讨论茶多酚对于口臭的疗效。方法:收集6位口臭患者的唾液,混合均匀后取4份5ml的样本,分别与阳性组、实验组、阴性组和空白组的TPY培养基混合后培养48h。最后进行16S rDNA V3-V4区基因组测序分析。结果:阳性组和实验组均能促进样本细菌OTU数的恢复。在门水平上,阳性组Firmicutes的相对丰度显著低于其余3组（P

Objective:To investigate the role of tea polyphenol in oral microecology in patients with fetid breath and the clinical effect of tea polyphenol in the treatment of fetid breath based on an analysis of bacterial community structure in samples.Methods:Saliva was collected from 6 patients with fetid breath and was mixed up thoroughly,and then 4 samples with a volume of 5 m L each were prepared.The 4 samples were mixed with the TPY medium in positive group,experimental group,negative group,and blank group,respectively,and were cultured for 48 hours.Genome sequencing was performed for the V3 and V...