期刊论文

中文

中国药房

1001-0408

2012

23

43

4052-4054

10.6039/j.issn.1001-0408.2012.43.08

本校为其他机构

目的:研究安胃丸对慢性胃炎模型大鼠的保护作用。方法:连续12周灌胃60%的乙醇(每周2次)、20mmol.L~(-1)的去氧胆酸钠,饮用0.05%的氨水以复制慢性胃炎大鼠模型。实验分为6组,即正常对照(等容生理盐水)、模型(等容生理盐水)、胃乃安(0.64g.kg~(-1))与安胃丸高、中、低剂量(12.24、 6.12、 3.06g.kg~(-1))组,灌胃给药,每天1次,连续30d。观察大鼠胃黏膜病理变化与胃酸、胃蛋白酶、游离黏液含量变化。结果:与模型组比较,安胃丸组游离酸、总酸、游离黏液含量与胃蛋白酶活性显著降低(P

OBJECTIVE：To study the protective effect of Anwei pills on chronic gastritis model rats.METHODS：Chronic gastritis model was established by intragastric administration of 60% ethanol,20 mmol·L-1 sodium deoxycholate and 0.05% ammonia water.Model rats were divided into 6 groups,i.e.normal control group（constant volume of normal saline）,model group（constant volume of normal saline）,Weinaian（0.64 g·kg-1） and Anwei pills high-dose,medium-dose and low-dose groups（12.24,6.12 and 3.06 g·kg-1）.They were given medicine once a day for consecut...