期刊论文

中文

中国药房

1001-0408

2015

03

339-343

国家自然科学基金资助项目（No,81473616） 湖南省科技厅重点项目（No.2013SK2025）

本校为第一机构

目的：系统评价他汀类药物干预高血压病炎症反应的疗效及安全性,以为临床治疗提供循证参考。方法：计算机检索Pub Med、EMbase、Cochrane图书馆、中国期刊全文数据库、万方数据库、维普数据库,收集他汀类药物干预高血压病炎症反应的随机对照试验（RCT）,提取资料和评价质量后,采用Rev Man 5.2统计软件进行Meta分析。结果：共纳入64项RCT,合计6 299例患者。Meta分析结果显示,试验组患者的收缩压[WMD=-6.33,95%CI（-8.33,-4.33）,P〈0.000]、舒张压[WMD=-3.60,95%CI（-5.14,-2.06）,P〈0.000]与对照组比较差异有统计学意义;C反应蛋白[WMD=-1.65,95%CI（-2.03,-1.26）,P〈0.000]、肿瘤坏死因子α[W...

OBJECTIVE： To evaluate therapeutic efficacy and safety of statin in the treatment of hypertension inflammatory reaction, and to provide evidence-based reference for clinical treatment. METHODS： Retrieved from PubMed, EMBase, Cochrane Library, CNKI, Wanfang and VIP, randomized controlled trials （RCT） about statins in the treatment of hypertension inflammatory reaction were collected, and Meta-analysis was performed by using Rev Man 5.2 statistical software after extracting information and evaluating quality. RESULTS： A total of 64 RCT were ...