OBJECTIVE:To optimize the preparation technology of Total iridoid glycosides liposome of Cornus officinalis,and to characterize it.METHODS:Total iridoid glycosides liposome of C.officinalis was prepared by reverse phase evaporation method.The contents of loganin and morroniside in Total iridoid glycosides liposome of C.officinalis were determined by HPLC.Using encapsulation rate of total saponins(total contents of loganin and morroniside)as index,main technology factors for the preparation of Total glycosides liposome of C.officinalis were scre...