期刊论文

中文

中国药房

1001-0408

2019

30

5

684-688

10.6039/j.issn.1001-0408.2019.05.22

湖南省教育厅重点项目(No.17A156) 湖南省中医药科研计划项目(No.201709).

本校为第一机构

目的:探讨醋炙乌药-木香对肝郁气滞型功能性消化不良(FD)模型大鼠胃排空及胃肠激素的影响.方法:将60只SD大鼠随机分为空白组(n=10)和造模组(n=50),造模组大鼠采用慢性应激束缚或食物剥夺或过度疲劳等多种手段复制肝郁气滞型FD模型.造模成功后,将造模组大鼠随机分为模型组(生理盐水)、醋炙乌药组(以生药量计为1.62 g/kg)、木香组(以生药量计为1.62 g/kg)、醋炙乌药-木香组(1:1,m/m,以生药量计为1.62 g/kg)和莫沙必利组(阳性对照,1.35 mg/kg),每组10只.各给药组大鼠每天灌胃相应药物1次,空白组和模型组大鼠灌胃等体积生理盐水,连续给药14 d.末次给药2 h后,采用酚红含量法检测各组大鼠的胃排空率和...

OBJECTIVE:To investigate the effects of Lindera aggregate of stir-baking with vinegar-Aucklandia lappa on gastric emptying and gastrointestinal hormones in functional dyspepsia liver depression and qi stagnation(FDLDQS)model rats.METHODS:Totally 60 SD rats were randomly divided into blank group(n=10)and modeling group(n=50);FDLDQS model was induced by chronic stress restraint or food deprivation or excessive fatigue in modeling group.After modeling,model rats were randomly divided into model group(normal saline),L.aggregate of stir-baking with ...