This research was funded by the National Natural Science Foundation of China (Grant no. 81673955), the Provincial Key Research and Development Project of Hunan (Grant no. 2022SK2012), the Provincial Natural Science Foundation Project of Hunan (Grant no. 2021JJ30495), and the Postgraduate Innovation Project of Hunan University of Chinese Medicine (Grant no. 2022CX153). CRediT authorship contribution statement Huizhen Zheng: Conceptualization, Data curation, Writing – original draft, Software, Visualization. Ziwei Yin: Investigation. Xi Luo: Methodology. Yingli Zhou: Validation. Fei Zhang: Resources. Zhihua Guo: Supervision, Writing – review & editing, acquisition.