N-methyl-2- （2-pyridyl）ethylamine hydrochloride was synthesized from 2-methylpyridine by four steps reaction. Best reaction conditions were found by orthogonal test. The optimum conditions were as follows, the amount ratio of 2-vinylpyridine and methyl amine was 1 ： 1.5, the reaction time was 8h, the reaction temperature was 105℃. The yield ratio of products was 86.8%. Results show that amount ratio was the main affecting factor. The structures of the target compound and ...
