Deep eutectic solvents(DES) are a new type of ionic liquids(ILs) analogs, compared with traditional organic solvents and ionic liquid, DESs are characterized by low toxicity, cheap, easy synthesis and biodegradability. Therefore, DESs have been widely concerned in many fields. In recent years, DESs have attracted much attention in the field of organic synthesis and are widely used as solvents, catalysts, reactants, etc. This paper summarizes the research on the application of DESs in organic synthesis reactions since 2012, focusing on the research progress in redox reactions, substitution reac...