Exosomal miR-151-3p in saliva: A potential non-invasive marker for gastric cancer diagnosis and prognosis modulated by Sijunzi decoction (SJZD) in mice

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yang, Ping;Lei, Huijun;Fu, Yue;Chen, Cheng;Tang, Li;...

通讯作者：

Li, L;Li, F

作者机构：

[Lei, Huijun; Tang, Li; Li, Liang; Yang, Ping; Fu, Yue; Chen, Cheng] Hunan Univ Chinese Med, Hunan Brain Hosp, Clin Med Sch, Dept Chinese & Western Integrat Med, Changsha 410007, Peoples R China.

[Lei, Huijun; Fu, Yue; Li, Liang; Chen, Guangyu; Xie, Mengzhou; Chen, Cheng; Xia, Shuaishuai] Hunan Univ Chinese Med, Prov Key Lab TCM Diag, Changsha 410208, Hunan, Peoples R China.

[Lei, Huijun; Fu, Yue; Li, Liang; Xie, Mengzhou; Chen, Cheng; Xia, Shuaishuai] Hunan Univ Chinese Med, Key Lab TCM Heart & Lung Syndrome Differentiat & M, Changsha 410208, Hunan, Peoples R China.

[Li, F; Li, Feng] Univ So Calif, Sch Dent, Los Angeles, CA 90089 USA.

[Guo, Yan; Yang, Ping] Xi An Jiao Tong Univ, Biomed Informat & Genom Ctr, Sch Life Sci & Technol, Key Lab Biomed Informat Engn Minist Educ, Xian 710049, Shaanxi, Peoples R China.

通讯机构：

[Li, F ] U

[Li, L ] H

Hunan Univ Chinese Med, Hunan Brain Hosp, Clin Med Sch, Dept Chinese & Western Integrat Med, Changsha 410007, Peoples R China.

Univ So Calif, Sch Dent, Los Angeles, CA 90089 USA.

语种：

英文

关键词：

Gastric cancer;Exosomal miRNAs;Sijunzi decoction (SJZD);Spleen deficiency syndrome;Exosomal miR-151-3p

期刊：

Heliyon

ISSN：

2405-8440

年：

2024

卷：

期：

页码：

e29169

DOI：

10.1016/j.heliyon.2024.e29169

机构署名：

本校为第一且通讯机构

院系归属：

中医诊断研究所

摘要：

Gastric cancer (GC) is one of the most prominent malignancies that originate in the epithelial cells of the gastric mucosa and is one of the main causes of cancer-related mortality worldwide. New circulating biomarkers of exosomal RNA might have great potential for non-invasive early prognosis of GC. Sijunzi Decoction (SJZD) is a typical representative formula of the method of benefiting Qi and strengthening the spleen in Traditional Chinese Medicine (TCM). However, the effects and mechanism of SJZD in treating GC remain unclear. This study looked for biomarkers of exosomal RNA for early progn...

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Exosomal miR-151-3p in saliva: A potential non-invasive marker for gastric cancer diagnosis and prognosis modulated by Sijunzi decoction (SJZD) in mice

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