Based on the total health expenditure data of Hunan Province from 2000 to 2017, using ARIMA model, this paper forecasts the total health expenditure, social health expenditure, personal health expenditure and cost structure of Hunan province from 2018 to 2022. The results show that: From 2018 to 2022, the total health expenditure of Hunan province tends to increase steadily;the government’s health investment is further increased, the social health expenditure is in a downward trend, and the control pressure of personal health expenditure is gr...