A ligation-triggered and protein-assisted fluorescence anisotropy amplification platform for sensitive and selective detection of small molecules in a biological matrix

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Chen, Meizi*;Wan, Bing;Du, Wei;Hu, Hongbo;Zeng, Long;...

通讯作者：

Chen, Meizi;Peng, Yongbo

作者机构：

[Wei, Zixiang; Peng, Yongbo; Chen, Meizi; Zeng, Long; Hu, Hongbo; Duan, Xintong; Liu, Jia; Chen, MZ; Peng, YB] First Peoples Hosp Chenzhou, Dept Gen Internal Med, Chenzhou 423000, Peoples R China.

[Wan, Bing] Nanjing Med Univ, Affiliated Jiangning Hosp, Dept Resp & Crit Care Med, Nanjing 211100, Peoples R China.

[Du, Wei] First Peoples Hosp Chenzhou, Dept Cardiol, Chenzhou 423000, Hunan, Peoples R China.

[Peng, Yongbo] Hunan Univ Chinese Med, Hunan Acad Chinese Med, Inst Chinese Med, Changsha 410208, Peoples R China.

[Tang, Li] Chongqing Univ Canc Hosp, Radiat Oncol Ctr, Chongqing Canc Inst, Chongqing 400030, Peoples R China.

通讯机构：

[Chen, MZ; Peng, YB] F

[Peng, Yongbo] H

First Peoples Hosp Chenzhou, Dept Gen Internal Med, Chenzhou 423000, Peoples R China.

Hunan Univ Chinese Med, Hunan Acad Chinese Med, Inst Chinese Med, Changsha 410208, Peoples R China.

语种：

英文

期刊：

RSC Advances

ISSN：

2046-2069

年：

2020

卷：

期：

页码：

21789-21794

DOI：

10.1039/c9ra09621c

基金类别：

Hunan Natural Science Foundation Youth Fund Project [2019JJ50021]; Key Research and Development Project of Hunan Province [2019 NK2101]; Natural science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK20191351]; Natural Science Foundation Project of CQ CSTCNatural Science Foundation Project of CQ CSTC [cstc2017jxjl130015, cstc2018jcyjAX0460]

机构署名：

本校为通讯机构

院系归属：

中医学院

摘要：

Effective detection of biomolecules is important for biological research and medical diagnosis. We here propose a ligation-triggered and protein-assisted fluorescence anisotropy amplification platform for sensitive and selective detection of small biomolecules in a complex biological matrix. In the proposed method, in the presence of target small molecules, FAM-labeled DNA 1 and biotin-labeled DNA2 were ligated to produce an integrated DNA. As a result, taking advantage of the extraordinary strong interaction between biotin and streptavidin, we...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

A ligation-triggered and protein-assisted fluorescence anisotropy amplification platform for sensitive and selective detection of small molecules in a biological matrix

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问