Dynamical regional activity in putamen distinguishes bipolar type I depression and unipolar depression

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成果类型：

期刊论文

作者：

Sun, Fuping;Liu, Zhening;Fan, Zebin;Zuo, Jing;Xi, Chang;...

通讯作者：

Yang, Jie

作者机构：

[Sun, Fuping; Liu, Zhening; Fan, Zebin; Yang, Jie; Xi, Chang] Cent South Univ, Natl Clin Res Ctr Mental Disorders, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

[Sun, Fuping; Liu, Zhening; Fan, Zebin; Yang, Jie; Xi, Chang] Cent South Univ, Dept Psychiat, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

[Zuo, Jing] Hunan Univ Chinese Med, Hunan Prov Brain Hosp, Sch Clin Med, Clin Med Res Ctr Hunan Prov Mental Behav Disorder, Changsha 410007, Hunan, Peoples R China.

通讯机构：

[Yang, Jie] C

Cent South Univ, Natl Clin Res Ctr Mental Disorders, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

Cent South Univ, Dept Psychiat, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

语种：

英文

关键词：

Bipolar type I depression;Dynamics;Fractional amplitude of low-frequency fluctuations;Machine learning;Unipolar depression

期刊：

Journal of Affective Disorders

ISSN：

0165-0327

年：

2022

卷：

297

页码：

94-101

DOI：

10.1016/j.jad.2021.10.021

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [82071506]; Natural Science Foundation of Hunan Province, ChinaNatural Science Foundation of Hunan Province [2021JJ40884]

机构署名：

本校为其他机构

院系归属：

临床医学院

摘要：

Objectives: Intrinsic human brain activity is time-varying and dynamic. However, there is still a lack of knowledge about the dynamic regional activity differences between unipolar depression (UD) and bipolar type I depression (BD-I), and whether their differential pattern can help to distinguish these two patient groups who are prone to misdiagnosis in clinical practice. Method: In this study, we used the dynamical fractional amplitude of low-frequency fluctuations (dfALFF) to examine the resting-state dynamical regional activity in 40 BD-I, 4...

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Dynamical regional activity in putamen distinguishes bipolar type I depression and unipolar depression

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