Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Jing;Tan, Yu-Fen;Zhou, Si-Qian;Liu, Shao;Wang, Wen-Xuan;...

作者机构：

[Li, Jing; Liu, Shao; Jiang, Yue-Ping] Cent South Univ, Xiangya Hosp, Dept Pharm, Changsha 410008, Hunan, Peoples R China.

[Liu, Ji-Kai] South Cent Minzu Univ, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China.

[Zhou, Si-Qian; Long, Hong-Ping] Hunan Univ Chinese Med, Hosp 1, Changsha 410007, Hunan, Peoples R China.

[Tan, Yu-Fen; Li, Jing; Liu, Shao; Jiang, Yue-Ping] Cent South Univ, Xiangya Hosp, Natl Clin Res Ctr Geriatr Disorders, Changsha 410008, Peoples R China.

[Wang, Wen-Xuan] Cent South Univ, Xiangya Sch Pharmaceut Sci, Changsha 410013, Peoples R China.

语种：

英文

关键词：

Enoic acids;Methylsuccinic acids;Neuroprotective activities;Xylaria nigripes;Xylariaceae

期刊：

Phytochemistry

ISSN：

0031-9422

年：

2023

卷：

210

页码：

113652

DOI：

10.1016/j.phytochem.2023.113652

基金类别：

National Natural Science Foundation of China [81903513, 82173713]; Natural Science Foundation of Hunan Province [2021JJ41000, 2021JJ40812]; China Postdoctoral Science Foundation [2020M682599]; Key R & D Program of Hunan Province [2022SK2031]

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

Three undescribed methylsuccinic acid derivatives, xylaril acids A-C, and two undescribed enoic acid derivatives, xylaril acids D-E, were isolated from the fungus Xylaria longipes. The structures of the undescribed compounds were deduced by spectroscopic means, including HRESIMS and 1D/2D NMR spectroscopy, as well as ECD calculations. The absolute configuration of xylaril acids A was further determined by single-crystal X-ray diffraction experiments. All the isolated compounds displayed neuroprotective activities against oxygen-glucose deprivation/reperfusion injury in PC12cells by enhancing c...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Neuroprotective methylsuccinic acid and enoic acid derivatives from the fungus Xylaria longipes

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问