期刊论文

Comparative study on distribution of pattern elements and results of different methods of pattern differentiation in cases of non-small cell lung cancer

中文

北京中医药大学学报

1006-2157

2019

42

9

787-792

10.3969/j.issn.1006-2157.2019.09.014

湖南省自然科学基金项目(No.2016JJ4067) 湖南省科技计划项目(No.22016SK2034) 抗肿瘤中药创制技术湖南省工程研究中心项目(No.湘发改高技2015-1085号)。

本校为第一机构

目的通过数据挖掘方法对非小细胞肺癌( NSCLC)病案进行挖掘,总结NSCLC的中医辨证规律,以期为NSCLC临床辨证用药提供参考。方法一方面挖掘出7 435份NSCLC病案的四诊信息,通过“文锋-III中医(辅助)诊疗系统”进行证素辨证;另一方面将临床医师记录的病案中医辨证拆分成单一证素。挖掘出非小细胞肺癌的证素分布规律,并比较临床医师辨证和“文锋-III中医(辅助)诊疗系统”辨证的差异。结果医师病案辨证结果表明,病位证素以脾( 1 910频次) 、肺( 1 608频次)为主,病性证素以气虚( 6 751频次) 、血瘀( 6 572频次) 、火(热、毒)( 6 331频次) 、阴虚( 5 657频次) 、痰( 1 242频次)等为主; “文锋-III中医(辅...

Objective To explore case records of non-small-cell lung cancer ( NSCLC) through data mining to obtain laws of TCM pattern differentiation of NSCLC,which provide reference for clinical pattern differentiation and treatment of NSCLC. Methods This study excavated information obtained by four diagnostic methods of 7435 non-small cell lung cancer cases,and conducted pattern element differentiation through the“Wenfeng-III Chinese Medicine ( Assisted) Diagnosis and Treatment System”. It also analyzed pattern elements from case records by clinicians...