期刊论文

中文

北京中医药大学学报

1006-2157

2023

46

6

790-800

10.3969/j.issn.1006-2157.2023.06.009

国家自然科学基金面上项目(No.81673585) 湖南创新型省份建设专项(No.2021SK2012)。

本校为第一机构

目的基于串联质量标签(TMT)标记的定量蛋白质组学研究黄精多糖改善顺铂诱导小鼠成肌细胞(C2C12细胞)肌管萎缩的蛋白质代谢轮廓,探讨黄精多糖的作用机制。方法将C2C12细胞培养至肌管,分为4组:正常组、顺铂组、黄精多糖...展开更多 目的基于串联质量标签(TMT)标记的定量蛋白质组学研究黄精多糖改善顺铂诱导小鼠成肌细胞(C2C12细胞)肌管萎缩的蛋白质代谢轮廓,探讨黄精多糖的作用机制。方法将C2C12细胞培养至肌管,分为4组:正常组、顺铂组、黄精多糖组、顺铂+黄精多糖组。按如下方法处理。正常组:不含血清的高糖DMEM培养基;顺铂组:不含血清的高糖DMEM培养基+50μmol/L顺铂;黄精多糖组:不含血清的高糖...

Objective To investigate the protein metabolism profile of Polygonatum cyrtonema Hua polysaccharide(PCP)on cisplatin-induced myotube atrophy in mouse myoblasts(C2C12 cells)by tandem mass tag(TMT)-labeled quantitative proteomics,and to further explore the mechanism of PC...MORE Objective To investigate the protein metabolism profile of Polygonatum cyrtonema Hua polysaccharide(PCP)on cisplatin-induced myotube atrophy in mouse myoblasts(C2C12 cells)by tandem mass tag(TMT)-labeled quantitative proteomics,and to further explore the mechanism of PCP....