Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses.

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成果类型：

期刊论文

作者：

Yuan, Ning;Chen, Yu;Xia, Yan;Dai, Jiacheng;Liu, Chunyu*

通讯作者：

Liu, Chunyu

作者机构：

[Yuan, Ning; Liu, Chunyu] Cent South Univ, Xiangya Hosp 2, Dept Psychiat, Changsha, Hunan, Peoples R China.

[Yuan, Ning; Liu, Chunyu] Cent South Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China.

[Yuan, Ning; Liu, Chunyu] Cent South Univ, Natl Clin Res Ctr Mental Disorders, Changsha, Hunan, Peoples R China.

[Yuan, Ning; Liu, Chunyu] Cent South Univ, Natl Technol Inst Mental Disorders, Changsha, Hunan, Peoples R China.

[Yuan, Ning; Liu, Chunyu] Hunan Univ Chinese Med, Sch Clin Med, Hunan Prov Brain Hosp, Dept Psychiat, Changsha, Hunan, Peoples R China.

通讯机构：

[Liu, Chunyu] C

[Liu, Chunyu] H

Cent South Univ, Xiangya Hosp 2, Dept Psychiat, Changsha, Hunan, Peoples R China.

Cent South Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China.

Cent South Univ, Natl Clin Res Ctr Mental Disorders, Changsha, Hunan, Peoples R China.

语种：

英文

期刊：

Translational Psychiatry

ISSN：

2158-3188

年：

2019

卷：

期：

页码：

1-13

DOI：

10.1038/s41398-019-0570-y

基金类别：

Hunan Provincial Health Commission Research Fund [B20180114]; Hunan Provincial Natural Science FoundationNatural Science Foundation of Hunan Province [2019JJ50312]; Research Fund of Hunan Provincial Brain Hospital [2017A01]; Diagnosis and Treatment Enhancement Project Fund of Hunan Provincial Severe Mental Illness; First Class Discipline of Clinical Medical School of Hunan University of Chinese Traditional Medicine; NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [1U01MH116489, 1R01MH110920, 1U01MH103340]; NSFCNational Natural Science Foundation of China (NSFC) [31871276]; NATIONAL INSTITUTE OF MENTAL HEALTHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute of Mental Health (NIMH) [U01MH103340, U01MH116489, R01MH110920, U01MH116489, R01MH110920, U01MH103340, U01MH116489, R01MH110920, U01MH116489] Funding Source: NIH RePORTER

机构署名：

本校为通讯机构

院系归属：

临床医学院

摘要：

Inflammation is a natural defence response of the immune system against environmental insult, stress and injury, but hyper- and hypo-inflammatory responses can trigger diseases. Accumulating evidence suggests that inflammation is involved in multiple psychiatric disorders. Using inflammation-related factors as biomarkers of psychiatric disorders requires the proof of reproducibility and specificity of the changes in different disorders, which remains to be established. We performed a cross-disorder study by systematically evaluating the meta-analysis results of inflammation-related factors in ...

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Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses.

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