期刊论文

Progress on Relationship between Vascular Smooth Muscle Cell Autophagy and Cardiovascular Disease and Relevant Pharmacological Intervention

中文

实用心脑肺血管病杂志

1008-5971

2017

25

10

1-4

10.3969/j.issn.1008-5971.2017.10.001

国家自然科学基金面上项目（31371161） 湖南省***项目基金（湘组2015 8号） 2015年湖南省大学生研究性学习与创新性试验计划项目

本校为第一机构

心血管疾病是危害人们身体健康的常见疾病之一,可损伤心脏及血管功能,血管平滑肌细胞（VSMC）功能在心血管疾病的发生发展过程中发挥着重要作用,而自噬在VSMC的生长、分化过程中发挥着至关重要的作用。本文主要综述了VSMC自噬与心血管疾病关系及药物干预的相关研究进展,以期为心血管疾病发病机制、病理学及新药开发研究提供参考。

Cardiovascular disease is one of common diseases that may endanger people＇s heatlth,it can cause heart and vascular function damage,and vascular smooth muscle cell（ VSMC） play an import role in the occurrence and development of cardiovascular disease,whereas autophagy play an import role in the growth and differentiation of VSMC. This paper reviewed the progress on relationship between VSMC autophagy and cardiovascular disease and relevant pharmacological intervention,in order to provide references for the researches about pathogenesis and pa...