Tang Biao, e-mail: biaotang@hnucm.edu.cn Scientific Research Fund of Hunan Provincial Education Department (No. 19B436); Hunan Provincial Innovation Foundation For Postgraduates (No. CX2018B515); Open Fund of the Domestic First-Class Discipline Construction Project of Integrated Traditional Chinese and Western Medicine of Hunan University of Chinese Medicine (No. 2018ZXYJH35); First-Class Discipline Construction Project of Basic Medicine in 13th Five-Year Plan of Hunan University of Chinese Medicine (06)