期刊论文

Study on anti-inflammatory active constituents from n-butanol extract of Acanthopanax henryi

中文

天然产物研究与开发

1001-6880

2021

33

04

598-606

10.16333/j.1001-6880.2021.4.009

江西省自然科学基金（20202BABL216070）； 赣南医学院校级科研项目（ZD201911,YB201910）； 湖南省自然科学基金（2019JJ40223）；

本校为其他机构

本文对糙叶五加果实正丁醇萃取物的抗炎活性成分进行研究。采用硅胶柱色谱、C18柱色谱、LH-20型羟丙基葡聚糖凝胶（Sephadex LH-20）柱色谱、半制备液相及重结晶等方法进行分离纯化,利用波谱分析结合理化性质鉴定化合物的结构。从糙叶五加果实正丁醇萃取部位中分离鉴定出17个化合物,分别为槲皮素-3-O-β-D-吡喃葡萄糖苷（1）、槲皮素-3-O-β-D-吡喃半乳糖苷（2）、芦丁（3）、1,3-双咖啡酰奎宁酸（4）、1,4-双咖啡酰奎宁酸（5）、1,5-双咖啡酰奎宁酸（6）、3,4-双咖啡酰奎宁酸（7）、3,5-双咖啡酰奎宁酸（8）、4,5-双咖啡酰奎宁酸（9）、绿原酸甲酯（10）、（2E,6S）-1-羟基-2,6-二甲基-2,7-辛二...

The anti-inflammatory active ingredients from n-butanol extract of the fruits of A.henryi were studied in this paper.The compounds were isolated and purified by silica gel,C_(18) and Sephadex LH-20 column chromatography,as well as Prep-HPLC and recrystallization methods.Their structures were identified on the basis of their physicochemical properties and spectroscopic data.As a result,seventeen compounds were obtained from A.henryi and the chemical structures were identified as quercetin-3-O-β-D-glucopyranoside (1),quercetin-3-O-β-D-galactopy...