New dibenzocyclooctadiene lignan from stems of Kadsura heteroclita

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成果类型：

期刊论文

作者：

Shehla, Nuzhat;Li, Bin;Zhao, Jianping;Cao, Liang;Jian, Yuqing;...

通讯作者：

Choudhary, MI

作者机构：

[Liao, Duan-fang; Choudhary, M. Iqbal; Shehla, Nuzhat; Li, Bin; Wang, Wei; Atta-ur-Rahman; Cao, Liang; Jian, Yuqing] Hunan Univ Chinese Med, TCM & Ethnomed Innovat & Dev Int Lab, Acad Atta Ur Rahman Belt & Rd Tradit Med Res Ctr, Sch Pharm, Changsha, Peoples R China.

[Choudhary, M. Iqbal; Shehla, Nuzhat; Wang, Wei; Atta-ur-Rahman] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi, Pakistan.

[Zhao, Jianping; Khan, Ikhlas A.] Univ Mississippi, Natl Ctr Nat Prod Res, Pharmaceut Sci Res Inst, University, MS 38677 USA.

通讯机构：

[Choudhary, MI ] H

Hunan Univ Chinese Med, TCM & Ethnomed Innovat & Dev Int Lab, Acad Atta Ur Rahman Belt & Rd Tradit Med Res Ctr, Sch Pharm, Changsha, Peoples R China.

Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi, Pakistan.

语种：

英文

关键词：

Kadsura heteroclita;Schisandraceae;dibenzocyclooctadiene lignan;antioxidative;cytotoxicity

期刊：

Natural Product Research

ISSN：

1478-6419

年：

2022

卷：

期：

页码：

8-17

DOI：

10.1080/14786419.2020.1758378

基金类别：

This work was supported by National Natural Science Foundation of China (No. 81374062 and 81673579), Ministry of Science and Technology of P.R. China (2018FY100703), and Hunan Science and Technology Department (2018SK 2110 and 2081).

机构署名：

本校为第一且通讯机构

院系归属：

药学院

摘要：

Kadsura heteroclita Roxb. Craib. (Schisandraceae), is a vine plant mainly distributed in southwest part of China. A new dibenzocyclooctadiene lignan, kadsulignan W (1), along with eleven known lignans (2–12) were isolated from chloroform soluble fraction of stems of Kadsura heteroclita. The structure of new lignan was elucidated by extensive spectroscopic techniques, namely one- and two-dimensional NMR spectroscopy, and HRESI-MS analysis. The absolute configuration of the biphenyl ring in the new dibenzocyclooctadiene lignan was discerned by c...

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New dibenzocyclooctadiene lignan from stems of Kadsura heteroclita

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