期刊论文

中文

针刺研究

1000-0607

2015

40

4

290-295

10.13702/j.1000-0607.2015.04.006

湖南省高校创新平台开放基金项目（No.12K088） 国家自然科学基金项目（No.81403487）

本校为第一机构

目的:观察电针"足三里"等穴对糖尿病胃轻瘫(DGP)大鼠胃肠运动和促生长素(ghrelin)mRNA、生长激素促分泌素受体(GHSR)mRNA表达的影响,探讨电针治疗DGP的可能机制。方法: 60只SD大鼠随机分为空白对照组、模型组、电针穴位组、电针非穴组、胃复安对照组,每组12只。采用单次腹腔注射2%链脲佐菌素配合高糖高脂饮食建立DGP大鼠模型。电针穴位组取大鼠"足三里""梁门""三阴交"穴;电针非穴组取"足三里""梁门""三阴交"穴位对照点;胃复安对照组予胃复安药液(1 mL/100 g)灌胃。用血糖仪测血糖,尿糖试纸测尿糖。治疗结束后以酚红为标记物,观察大鼠胃排空率及小肠推进率;实时荧光定量多聚核苷酸链式反应法检测...

OBJECTIVE: To observe the effect of electroacupuncture (EA) stimulation of "Zusanli" (ST 36), "Liangmen" (ST 21) and "Sanyinjiao" (SP 6) on gastrointestinal motility and expression of ghrelin and growth hormone secretagogue receptor (GHSR) mRNA in diabetic gastroparesis (diabetic gastroparesis, DGP) rats, so as to explore its mechanism underlying improvement of diabetic gastroparesis. METHODS: Sixty SD rats were randomly and equally divided into normal control, model, EA acupoint, EA non-acupoint, medication (metoclopramide) groups (n = 12 rat/group). The DGP model was established by intraperi...