期刊论文

中文

针刺研究

1000-0607

2016

41

3

189-196

10.13702/j.1000-0607.2016.03.001

No.81273828:国家自然科学基金 81273830:国家自然科学基金 No.2013CB531904:国家重点基础研究发展计划（973计划）

本校为第一机构

目的:观察电针"内关"-"间使"穴对心肌缺血(MI)大鼠疑核胆碱能神经元、心率变异性(HRV)高频成分(HF)等变化的影响,分析电针改善MI的机制。方法:雄性Wistar大鼠随机分为正常组、模型组、内关-间使组、三阴交-地机组,每组12只。结扎冠状动脉左前降支复制MI模型。MI后1、2、3 d分别给予两电针组动物电针各30 min。用生理信号采集系统记录心电图(ECG),并分析心率(HR)、ECG-J点高度和HRV的HF、低频(LF)成分值;用酶联免疫法检测血清磷酸肌酸激酶(CK-MB)、乳酸脱氢酶(LDH 1)、内皮素(ET)的含量,用免疫荧光法检测延髓疑核区乙酰胆碱转移酶(ChAT)、囊泡状乙酰胆碱转运体(VAChT)和c-fos的表达。结果:与正常...

OBJECTIVE: To observe the effect of electroacupuncture (EA) stimulation of "Neiguan" (PC 6)-"Jianshi" (PC 7) on ischemic myocardial injury in myocardial ischemic (MI) rats, so as to explore its mechanism underlying improvement of MI. METHODS: A total of 48 male Wistar rats were randomly divided into normal, MI model, PC 6-PC 7, Sanyinjiao-Diji (SP 6-SP 8) groups (n=8 in each group for physiological experiments, n=4 in each group for immunoflorescence stain). The MI model was established by occlusion of the anterior descending branch of the left coronary artery. Electrocardiogram (ECG) of the n...