期刊论文

Herbal cake-separated moxibustion relieves aspirin induced gastric mucosal injury by activating Nrf2/ARE/HO-1 signaling in rats

中文

针刺研究

1000-0607

2023

48

8

773-781

10.13702/j.1000⁃0607.20220501

No.81704185:国家自然科学基金 No.2021JJ40396:湖南省自然科学基金项目 No.19C1397:湖南省教育厅科学研究项目

本校为第一机构

目的:探讨隔药饼灸是否通过激活核因子E2相关因子2(Nrf2)/抗氧化反应元件(ARE)/血红素加氧酶-1(HO-1)信号通路修复阿司匹林诱导的胃黏膜损伤。方法:SD大鼠随机分为空白对照组、模型组、隔药饼灸穴位组、空白+...展开更多 目的:探讨隔药饼灸是否通过激活核因子E2相关因子2(Nrf2)/抗氧化反应元件(ARE)/血红素加氧酶-1(HO-1)信号通路修复阿司匹林诱导的胃黏膜损伤。方法:SD大鼠随机分为空白对照组、模型组、隔药饼灸穴位组、空白+抑制剂组、模型+抑制剂组、隔药饼灸+抑制剂组,每组20只。阿司匹林(150 mg/kg)灌胃诱导复制胃黏膜损伤模型。隔药饼灸穴位组和隔药饼灸+抑制剂组施隔药饼灸“足三里”“中...

Objective To investigate whether herbal cake-separated moxibustion can activate nuclear factor erythroid 2-related factor 2(Nrf2)/antioxidant responsive element(ARE)/hemeoxygenase-1(HO-1) signaling pathway to repair aspirin induced gastric mucosal injury(GMI) in rats.Me...MORE Objective To investigate whether herbal cake-separated moxibustion can activate nuclear factor erythroid 2-related factor 2(Nrf2)/antioxidant responsive element(ARE)/hemeoxygenase-1(HO-1) signaling pathway to repair aspirin induced gastric mucosal injury(GMI) in rats.Meth...