The potential combinational effect of miR-34a with celecoxib in osteosarcoma

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Chen, Xia;Peng, Dan;Shen, Yi;Liu, Bo;Zhou, Hongkang;...

通讯作者：

Huang, Jufang;Tao, Huai（陶怀）

作者机构：

[Liu, Bo; Chen, Xia; Shen, Yi; Peng, Dan] Cent S Univ, Xiangya Hosp 2, Dept Orthoped, Changsha, Hunan, Peoples R China.

[Huang, Jufang; Zhou, Hongkang] Cent S Univ, Sch Basic Med Sci, Dept Anat & Neurobiol, Changsha 410013, Hunan, Peoples R China.

[Tao, Huai] Hunan Univ Chinese Med, Dept Biochem & Mol Biol, Changsha 410208, Hunan, Peoples R China.

[Tao, Huai] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, Changsha, Hunan, Peoples R China.

通讯机构：

[Tao, Huai] H

[Huang, Jufang] C

Cent S Univ, Sch Basic Med Sci, Dept Anat & Neurobiol, Changsha 410013, Hunan, Peoples R China.

Hunan Univ Chinese Med, Dept Biochem & Mol Biol, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

MiR-34a;celecoxib;invasion;migration;osteosarcoma;proliferation

期刊：

Anti-Cancer Drugs

ISSN：

0959-4973

年：

2017

卷：

期：

页码：

888-897

DOI：

10.1097/CAD.0000000000000530

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81503276]; National Key Research and Development Program of China [2016.YFC1201800]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [15C1044]; Research Foundation of Stem Cell Regulation and Application of Hunan University of Chinese Medicine [2013GXB01]; Scientific Research Starting Foundation of Hunan University of Chinese Medicine [9982-1001-010]

机构署名：

本校为通讯机构

院系归属：

医学院

中医学院

药学院

摘要：

Advanced osteosarcoma (OS) is usually treated by preoperative and postoperative chemotherapy, but there are a very limited number of active agents. Celecoxib (Cel) is a COX-2-selective nonsteroidal anti-inflammatory drug and its antitumoral effect has been shown widely in a variety of cancers including OS cells in vitro. However, the potential combinational effect of Cel with other biological therapy has not been reported in OS cells. In this study, the effects of Cel, miR-34a mimics, and their combination on cell proliferation (MTT assay), mig...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

The potential combinational effect of miR-34a with celecoxib in osteosarcoma

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问