The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance

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成果类型：

期刊论文

作者：

Dai, Bing;Wu, Qinxuan;Zeng, Chengxi;Zhang, Jiani;Cao, Luting;...

通讯作者：

Xiao, Zizeng

作者机构：

[Dai, Bing] Hunan Univ Tradit Chinese Med, Affiliated Hosp 1, Shaoshan Rd, Changsha 410007, Hunan, Peoples R China.

[Wu, Qinxuan] Changsha Med Univ, Changsha 410219, Hunan, Peoples R China.

[Zeng, Chengxi] Changsha Social Work Coll, Changsha 410000, Hunan, Peoples R China.

[Cao, Luting; Yang, Menglin; Xiao, Zizeng; Zhang, Jiani] Hunan Univ Tradit Chinese Med, Changsha 410208, Hunan, Peoples R China.

[Xiao, Zizeng] Hunan Univ Tradit Chinese Med, Coll Integrat Med, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Xiao, Zizeng] H

Hunan Univ Tradit Chinese Med, Coll Integrat Med, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

*Liuwei Dihuang decoction;*Loganin(:C(17)H(26)O(10),390.38);*Morroniside(C(17)H(26)O(11),402.38);*PI3K/Akt signaling pathway;*Paeonoside(C(23)H(28)O(11), 480.47);*Sweroside(C(16)H(22)O(9),358.34);*Type 2 diabetes mellitus

期刊：

Journal of Ethnopharmacology

ISSN：

0378-8741

年：

2016

卷：

192

页码：

382-389

DOI：

10.1016/j.jep.2016.07.024

基金类别：

Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [13JJ3096]

机构署名：

本校为第一且通讯机构

院系归属：

中医学院

第一中医临床学院

中西医结合学院

药学院

摘要：

Ethnopharmacological relevance: Liuwei Dihaung decoction (LWDHT) is a well-known classic traditional Chinese medicine formula, consists of six herbs including Rehmannia glutinosa Libosch.(family: Scrophulariaceae), Cornus officinalis Sieb.(family: Cornaceae), Dioscorea opposite Thunb.(family: Dioscoreaceae), Alisma orientale(G. Samuelsson) Juz (family: Alismataceae), Poria cocos (Schw.) Wolf (family: Polyporaceae) and Paeonia suffruticosa Andrews (family: Paeoniaceae). It has been used in the treatment of many types of diseases with signs of deficiency of Yin in the kidneys in China clinically...

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The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance

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