Undescribed phenylpropanoid and a dimeric sesquiterpenoid possessing a rare cyclobutane ring from Tinospora sinensis

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期刊论文

作者：

Parveen, Abidah;Ali, Zulfiqar*;Fantoukh, Omer;Alhusban, Manal;Wang, Wei;...

通讯作者：

Ali, Zulfiqar;Khan, IA

作者机构：

[Ali, Zulfiqar; Chittiboyina, Amar G.; Khan, Ikhlas A.; Parveen, Abidah; Alhusban, Manal] Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, University, MS 38677 USA.

[Fantoukh, Omer; Parveen, Abidah; Alhusban, Manal; Khan, Ikhlas A.] Univ Mississippi, Sch Pharm, Dept Biomol Sci, Div Pharmacognosy, University, MS 38677 USA.

[Parveen, Abidah] Abbottabad Univ Sci & Technol, Dept Pharmaceut Sci, Havelian, Kpk, Pakistan.

[Fantoukh, Omer] King Saud Univ, Coll Pharm, Dept Pharmacognosy, Riyadh, Saudi Arabia.

[Wang, Wei] Hunan Univ Chinese Med, Sch Pharm, TCM & Ethnomed Innovat & Dev Lab, Changsha, Hunan, Peoples R China.

通讯机构：

[Ali, Z; Khan, IA ] U

Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, University, MS 38677 USA.

语种：

英文

关键词：

Tinospora sinensis;Menispermaceae;isolation;NMR;tinosposinoside;cordifolioside C

期刊：

Natural Product Research

ISSN：

1478-6419

年：

2020

卷：

期：

页码：

3955-3962

DOI：

10.1080/14786419.2020.1752207

基金类别：

This research is supported by “Science Based Authentication of Dietary Supplements” funded by the United States Food and Drug Administration grant number 2U01FD004246.

机构署名：

本校为其他机构

院系归属：

药学院

摘要：

A rare dimeric sesquiterpenoid (tinosposinoside, 1) and a phenylpropanoid (cordifolioside C, 2), two undescribed metabolites, were isolated from the methanolic extract of the stems of Tinospora sinensis together with thirteen known compounds. This is the second example of a sesquiterpene dimer where two monomers linked together through a cyclobutane ring, possibly generated through [2 + 2] cycloaddition. The structures of 1 and 2 were elucidated by NMR and mass techniques. ©...

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Undescribed phenylpropanoid and a dimeric sesquiterpenoid possessing a rare cyclobutane ring from Tinospora sinensis

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