Objective To investigate the effect of Bimin tablet on morphological changes of the nasal mucosa of guinea pigs with allergic rhinitis. Methods Toluene 2,4-diisocyanate (TDI) was used intranasally as allergen to induce guinea pigs models with hypersensitivity and Xisimin was used as the positive control. The morphological changes of the nasal mucosa in guinea pigs were observed. Results Bimin tablet could reduce the symptoms such as nasal discharge and sneezing, inhibit inflammatory cell infiltration and promote the restoration of the nasal mucosa. The effect of Bimin tablet lasted a longer ti...