The endoplasmic reticulum, being as an intracellular mesangial organelle, maintains homeostasis by participating in the synthesis, folding, maturation, and post- translational modification of secreted and transmembrane proteins, which is closely related to the development of disease. When the endoplasmic reticulum environment is disturbed,folding or misfolding of protein starts,and followed with the activation of the endoplasmic reticulum stress. The latter can regulate the neuron's apoptosis and autophagy. This article aims to explore the relationship between neuronal apoptosis and autophagy ...
