期刊论文

Research on Medication Rule of Modern Famous Doctors in Treating Angina Pectoris Based on Xiongbi Xintong Gujin Mingjia Yanan Quanxi

中文

中药新药与临床药理

1003-9783

2021

32

09

1406-1411

10.19378/j.issn.1003-9783.2021.09.024

国家自然科学基金面上项目（81973753）； 湖南省自然科学基金面上项目（2018JJ2291）； 研究生质量工程项目（2018CX28,2020CX57）；

本校为第一机构

目的探讨近现代名医治疗心绞痛的用药规律,为临床选方用药提供借鉴。方法整理《胸痹心痛古今名家验案全析》中近现代名医论治心绞痛的经验效方,将复方录入Excel 2010建立数据库,采用古今医案云平台(V2.3)进行频次分析、关联规则、聚类分析,采用SPSS Statistics 25.0进行因子分析。结果共纳入86位医家,254首经验方,涉及中药266味。高频药物有丹参、瓜蒌、薤白、甘草、半夏等。药性多用温,药味以苦、甘为主,归经以肺、心、脾为要,功效类别以补虚药、活血化瘀药等最为多见。关联规则获得“薤白-瓜蒌”“半夏-薤白”“半夏-瓜蒌”等11个核心药对。因子分析将药物分为6个公因子,涵盖瓜蒌薤白白酒汤、...

Objective To explore the medication rules of modern famous doctors in treating angina pectoris,and to provide reference for selection of clinical prescription. Methods The empirical prescriptions used for angina pectoris by modern famous doctors in Xiongbi Xintong Gujin Mingjia Yanan Quanxi were sorted out, and the compound prescriptions were entered into excel 2010 to establish a database. The ancient and modern medical record cloud platform(V2.3)was used for frequency analysis,association rules and cluster analysis. SPSS Statistics 25.0 was used for factor analysis. Results A total of 254 em...