National Natural Science Foundation of China [82204924]; Hunan Province Postgraduate Scientific Research Innovation Project [CX20220773]; Hunan Provincial Depart-ment of Education general project [22C0195]
机构署名：
本校为第一机构
院系归属：
医学院
药学院
湘杏学院
摘要：
CONTEXT: Aging is a major risk factor for various neurodegenerative diseases, and ferroptosis has been identified as an important mode of cell death during accelerated aging. As the main component of the edible plant YuZhu in China, Polygonatum polysaccharide (POP) is an important natural compound with anti-aging properties. OBJECTIVE: To evaluate the anti-aging effects of POP and the underlying molecular mechanisms involved and to evaluate the overall anti-aging effects of POP on cognitive impairment due to accelerated aging. MATERIALS AND METHODS: A D-galactose (D-gal)-induced accelerated ag...
