Combinative Approaches of Chemistry, Pharmacology and Toxicology for the Optimal Pharmaceutical Preparation of an Anti-arthritic Chinese Medicine Formulation QFJBT

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成果类型：

期刊论文

作者：

张婷;余黄合;林也;李鑫;唐琳;...

通讯作者：

CAI, X.

作者机构：

[蔡雄] Institute of Innovation and Applied Research in Chinese Medicine, Hunan University of Chinese Medicine, Hunan, Changsha, 410208, China

[陈聪; 李鑫; 彭清华; 宋厚盼] School of Basic Chinese Medical Sciences, Hunan University of Chinese Medicine, Hunan, Changsha, 410208, China

[王炜] School of Pharmaceutical Sciences, Hunan University of Chinese Medicine, Hunan, Changsha, 410208, China

[唐琳] School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangdong, Guangzhou, 510224, China

[刘良] State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, 999078, Macau

通讯机构：

[CAI, X.] I

Institute of Innovation and Applied Research in Chinese Medicine, Hunan, China

语种：

中文

关键词：

青附蠲痹汤;类风湿关节炎;制备工艺;质量控制;安全性;抗炎镇痛

关键词(英文)：

Anti-inflammatory and antinociceptive effects;Pharmaceutical preparation;QFJBT;Quality control;Rheumatoid arthritis;Safety profile

期刊：

数字中医药(英文)

ISSN：

2096-479X

年：

2018

卷：

期：

页码：

289-301

DOI：

10.1016/S2589-3777(19)30054-0

基金类别：

We thank for the funding support from the National Natural Science Foundation of China (No. 81704065), China Postdoctoral Science Foundation (No. 2016M600632 and No. 2017T100604), Hunan Provincial Natural Science Foundation (No. 2017JJ3239 and No. 2018JJ2293), Hunan Education Department’s Science & Research Project (No. 17K069), Hunan Provincial Science & Research Project of Chinese Medicine (No. 201790), and National First-class Disciple Construction Project of Chinese Medicine of Hunan University of Chinese Medicine.

机构署名：

本校为第一机构

院系归属：

医学院

中医学院

药学院

摘要：

Objective Qing Fu Juan Bi Tang (QFJBT) is an anti-arthritic Chinese medicine formula consisting of five herbs: Aconiti Lateralis Radix Praeparata (Fu Zi, 附子), Sinomenii Caulis (Qing Feng Teng, 青风藤), Astragali Radix (Huang Qi, 黄芪), Paeoniae Radix Alba (Bai Shao, 白芍) and Moutan Cortex (Mu Dan Pi, 牡丹皮), which have well-established histories of use for treatment of rheumatic and arthritic diseases. We intended to establish the optimized and standardized pharmaceutical procedures and manufacturing processes for the pilot production of QF...

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Combinative Approaches of Chemistry, Pharmacology and Toxicology for the Optimal Pharmaceutical Preparation of an Anti-arthritic Chinese Medicine Formulation QFJBT

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