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Electroacupuncture Relieves Suppression of Autophagy in Interstitial Cells of Cajal of Diabetic Gastroparesis Rats

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成果类型:
期刊论文
作者:
Wei, Xing;Lin, Yaping;Zhao, Dongfeng;Xiao, Xiaojuan;Chen, Qiao;...
通讯作者:
Peng, Yan
作者机构:
[Wei, Xing; Xiao, Xiaojuan; Peng, Yan; Zhao, Dongfeng; Lin, Yaping] Hunan Univ Chinese Med, Coll Acupuncture & Moxibust & Tui Na, Domest First Class Discipline Construct Project C, Changsha 410000, Peoples R China.
[Chen, Qiao; Chen, Siyi] Hunan Univ Chinese Med, Sch Med, Changsha 410000, Peoples R China.
通讯机构:
[Peng, Yan] H
Hunan Univ Chinese Med, Coll Acupuncture & Moxibust & Tui Na, Domest First Class Discipline Construct Project C, Changsha 410000, Peoples R China.
语种:
英文
期刊:
Canadian Journal of Gastroenterology and Hepatology
ISSN:
2291-2789
年:
2020
卷:
2020
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81774431]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
针灸推拿与康复学院
摘要:
Background. The incidence of diabetic gastroparesis (DGP) is mainly blamed to abnormity of interstitial cells of Cajal (ICCs). Autophagy could degrade damaged proteins and organelles to keep intracellular homeostasis, and it could directly influence structure and number of cells. In this study, we aimed to figure out the relationship between DGP and autophagy of ICCs. Methods. Sixty Sprague-Dawley (SD) rats were randomly divided into normal control group (NC, 10) and modeling group (50). Rats in the modeling group were injected 2% streptozotoci...

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