Berberine and ginsenoside Rg3 act synergistically via the MAPK/ERK pathway in nasopharyngeal carcinoma cells

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Fangliang;Hu, Jing;Dai, Na;Song, Lan;Lin, Ting;...

通讯作者：

He, Yingchun;Liao, Duan-fang

作者机构：

[Zhou, Fangliang; He, Yingchun; Song, Lan] Hunan Univ Chinese Med, Coll Med, Changsha 410208, Peoples R China.

[Hu, Jing; Liu, Jie; Zhou, Fangliang; Dai, Na; Lin, Ting; Li, Kairui; He, Yingchun; Song, Lan] Hunan Prov Key Lab Prevent & Treatment Ophthalmol, Changsha 410208, Peoples R China.

[Peng, Zhuang; Liao, Duan-fang; Zhou, Fangliang; Song, Lan] Hunan Prov Key Lab Qual Evaluat Bulk Herbs, Changsha 410208, Peoples R China.

[Hu, Jing; Liu, Jie; Zhou, Fangliang; Dai, Na; Lin, Ting; Li, Kairui; He, Yingchun] Hunan Prov Engn & Technol Res Ctr Prevent & Treat, Changsha 410208, Peoples R China.

[He, Yingchun; Liao, DF] Hunan Univ Chinese Med, 300 Xueshi Rd, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[He, YC; Liao, DF] H

Hunan Univ Chinese Med, 300 Xueshi Rd, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

Berberine;Ginsenoside Rg3;Synergistic action;Nasopharyngeal carcinoma cells;MAPK/ERK Pathway

期刊：

Journal of Functional Foods

ISSN：

1756-4646

年：

2020

卷：

页码：

103802-

DOI：

10.1016/j.jff.2020.103802

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81874408]; Natural Science Foundation of HunanNatural Science Foundation of Hunan Province [2017JJ3246, 2019JJ40216]; Excellent Youth Fund of Hunan Provincial Education Department [19B439]; Natural Science Foundation of GuangxiNational Natural Science Foundation of Guangxi Province [2015GXNSFEA139003]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Herein, we investigated the effects of combining berberine (Ber; the major active constituent of Rhizoma coptidis) with ginsenoside Rg3 (Rg3; an active ingredient of Panax ginseng) on the proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells, and explored the underlying mechanism. Combining Ber with Rg3 synergistically inhibited the proliferation of NPC CNE2 cells in vitro and in vivo. Additionally, Ber combined with Rg3 induced apoptosis by promoting the expression of apoptosis-related protein Box, and inhibiting the expression of Survivin, PCNA and anti-apoptotic protein Bcl-2....

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Berberine and ginsenoside Rg3 act synergistically via the MAPK/ERK pathway in nasopharyngeal carcinoma cells

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问