期刊论文

Research Progress of Western and Chinese Medicine in Oral Mucosa Fibrosis

中文

世界核心医学期刊文摘(眼科学分册)

1671-3141

2016

14

31-33

国家自然基金项目（No.81373701）；

本校为第一机构

口腔黏膜下纤维化英文名称oral submucous fibrosis,简称OSF。其是一种慢性、隐匿性、具有癌变倾向的口腔黏膜疾病。临床以患者进食刺激性食物时口内疼痛、口腔黏膜苍白僵硬、严重者张口受限、进食困难为特征。近年来该病发生呈年青化趋势,在性别方面男性更为突出,可能与吸烟、酗酒等生活习惯密切相关。据估计,世界范围内约有8亿人咀嚼槟榔,其中约有2500万OSF患者,故OSF已成为世界许多地域中居住人群所面临的公共健康问题之一。本病发病机制复杂至今仍不明确,许多研究认为与代谢障碍、遗传、免疫等有关。因咀嚼槟榔是导致OSF的最主要因素,中医则认为:痰瘀互结为本病病机关键,中医素有"久病必瘀"...

submucous fibrosis oral (OSF) is a kind of chronic, occult and malignant oral mucosal disease. Clinical patients with eating food to stimulate the mouth pain, oral mucosa pale and stiff, severe restriction of mouth opening,eating difficulties for the characteristics of. A young male occurrence of the disease, development, life and think that smoking and alcohol habits are closely related. It is estimated that about 800 million people worldwide chewing nut, which has about 25 million OSF patients, so OSF has become one of the public health probl...