One of the major challenges in coronary artery disease diagnosis is the identification of reliable clinical bio- markers from normal blood samples. Circulating miRNAs are small non-coding RNA existing in body fluids, because of their stability and often tissue-and disease-specific expression and high sensitivity; they could be new potential non-inva- sive biomarkers of CAD. It can lay the foundation for screening feasible clinical circulating miRNA biomarkers in the fu- ture, through reviewing the circulating miRNAs associated with CAD in blood...