This study was supported by the Fundamental Research Funds for the Central Universities of Central South University (no 2016zzt-s558) and the New Xiangya Talent Projects of the Third Xiangya Hospital of Central South University (20150201, JY201623, JY201615).
机构署名:
本校为通讯机构
摘要:
MiR-130b and SAM and SH3 domain containing 1 (SASH1) play an important role in many types of human cancers. The aim of our research was to study their interactions in the process of the proliferation and aggressiveness of oesophageal squamous cell carcinoma (ESCC) cells. Microarray analysis was done to screen the differentially expressed genes in the ESCC tissues. miR-130b and SASH1 mRNA levels in the ESCC tissues and cells were detected by qRT-PCR. Dual luciferase reporter system was used to verify the target relationship between miR-130b and ...