期刊论文

Chen, Yinghui

英文

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS

1871-5273

2017

16

6

686-693

10.2174/1871527316666170505123956

This investigation was supported by grants from the Traditional Chinese Medicine Research Fund of the Shanghai Municipal Commission of Health and Family Planning (2014JP007A) to YC.

本校为其他机构

Background: Status epilepticus (SE), is characterized by high mortality and morbidity, which can cause neuronal injury, neuronal death and alteration of neuronal networks, Recently, inflammation was shown to play a significant role in SE pathogenesis. And miRNA-146a has been shown to be involved in inflammation and to inhibit inflammatory cytokines through NF-κB pathway. In our study, we investigated the relationship between inflammation and miR-146a expression. Method: The SE rat model was induced by lithium-pilocarpine. Hematoxylin and eosin...