Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Yang, Rui;Su, Xiaozhe;Liu, Ziqi;Shao, Shuai;Wang, Yinhuai;...

通讯作者：

Su, Hao;He, HQ

作者机构：

[He, HQ; Shao, Shuai; Su, Hao; He, Haiqing; Yang, Rui; Wang, Yinhuai] Cent South Univ, Dept Urol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

[Yang, Rui; Shao, Shuai] Cent South Univ, Xiangya Sch Med, Changsha 410013, Hunan, Peoples R China.

[Su, Xiaozhe] Wuhan Univ, Dept Urol, Renmin Hosp, Wuhan 430060, Peoples R China.

[Liu, Ziqi] Hunan Univ Chinese Med, Dept Acupuncture & Moxibust, Hosp 1, Changsha 410007, Hunan, Peoples R China.

通讯机构：

[He, HQ ; Su, H] C

Cent South Univ, Dept Urol, Xiangya Hosp 2, Changsha 410011, Hunan, Peoples R China.

语种：

英文

关键词：

Survival;Prognosis;Drug therapy;Acute kidney injury;Intensive care unit;Nomogram

期刊：

EUROPEAN JOURNAL OF MEDICAL RESEARCH

ISSN：

0949-2321

年：

2025

卷：

期：

页码：

1-13

DOI：

10.1186/s40001-025-02300-4

基金类别：

Scientific Research Launch Project for new employees of the Second Xiangya Hospital of Central South University

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

针灸推拿与康复学院

摘要：

Acute kidney injury (AKI) is defined by a sharp decrease in the estimated glomerular filtration rate (eGFR). However, the impact of medication history on the survival of AKI patients has received little attention. Hence, it is necessary to investigate the potential of medication history as a predictor of survival outcomes among AKI patients in the intensive care unit (ICU). Critically ill AKI patients were sourced from the MIMIC-IV database. To ascertain significant, drug-related, independent predictors of survival, univariate Cox analysis and ...

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Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram

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