Pluronic F127-liposome-encapsulated curcumin activates Nrf2/Keap1 signaling pathway to promote cell migration of HaCaT cells

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Quan;Cai, Xu;Huang, Ying;Zhou, Youliang

通讯作者：

Youliang Zhou

作者机构：

[Zhou, Quan; Zhou, Youliang] Hunan Univ Chinese MedicineYuhua Dist Hunan Prov, Dept Emergency, Hosp 1, 95 Shaoshan Middle Rd, Changsha 410000, Peoples R China.

[Cai, Xu] Hunan Univ Chinese Med, Dept Orthopaed, Hosp 1, Changsha 410000, Hunan, Peoples R China.

[Huang, Ying] Shenzhen Sami Int Med Ctr, Dept Neurosurg, Shenzhen 518038, Guangdong, Peoples R China.

通讯机构：

[Youliang Zhou] D

Department of Emergency, The First Hospital of Hunan University of Chinese MedicineYuhua DistrictHunan Province, No. 95, Shaoshan Middle Road, Changsha, China

语种：

英文

关键词：

Curcumin;Liposome;Migration;Nrf2/Keap1 signaling pathway;Pluronic F127;Wound healing

期刊：

Molecular and Cellular Biochemistry

ISSN：

0300-8177

年：

2023

卷：

478

期：

页码：

241-247

DOI：

10.1007/s11010-022-04481-6

基金类别：

This work was supported by Hunan Provincial Health Commission (202104101005) and Hunan Administration of traditional Chinese Medicine (2021227).

机构署名：

本校为其他机构

院系归属：

第一中医临床学院

摘要：

Curcumin (CUR) is an extract of Curcuma longa Linn., which has various pharmacological activities. The instability, low water solubility and bioavailability of CUR greatly limit its clinical application. This work prepared Pluronic F127-liposome-encapsulated curcumin (CUR-LIP-F127) and explored its functional role in wound healing. Liposome-encapsulated curcumin (CUR-LIP) and CUR-LIP-F127 were prepared. Human keratinocyte cell line (HaCaT) was treated with CUR, Pluronic F127-liposome (LIP-F127) and CUR-LIP-F127, or combined with ML385 (Nrf2 inhibitor). The expression of mRNAs and proteins was ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Pluronic F127-liposome-encapsulated curcumin activates Nrf2/Keap1 signaling pathway to promote cell migration of HaCaT cells

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问