Effects of Cornu Bubali (CB) on the Adhesion of Leukocyte and Endothelial Cells

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成果类型：

期刊论文

作者：

Li, Haixia;Xiao, Zhenghui*;Tian, Xuefei*;Wang, Paoqiu;Long, Yan;...

通讯作者：

Xiao, Zhenghui;Tian, Xuefei

作者机构：

[Liu, Chunlei; Long, Yan; Luo, Wei; Li, Haixia; Wang, Paoqiu] Hunan Childrens Hosp, Dept Rehabil Integrated Chinese & Western Med 3, Changsha 410007, Hunan, Peoples R China.

[Li, Haixia] Hunan Univ Chinese Med, Changsha 410208, Hunan, Peoples R China.

[Xiao, Zhenghui] Hunan Childrens Hosp, Emergency Ctr, Changsha 410007, Hunan, Peoples R China.

[Tian, Xuefei] Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.

[Zheng, Mincui; Kuang, Wenyong] Hunan Childrens Hosp, Dept Hematol, Changsha 410007, Hunan, Peoples R China.

通讯机构：

[Xiao, Zhenghui; Tian, Xuefei] H

Hunan Childrens Hosp, Emergency Ctr, Changsha 410007, Hunan, Peoples R China.

Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

Cornu Bubali;Leukocytes;Adhesion;Intercellular Adhesion Molecule;Tumor Necrosis Factor Alpha (TNF-alpha);Notch

期刊：

Journal of Biomaterials and Tissue Engineering

ISSN：

2157-9083

年：

2020

卷：

期：

页码：

554-561

DOI：

10.1166/jbt.2020.2324

基金类别：

64th General Project of China Postdoctoral Science Foundation [2018M642982]; Major Project of Hunan Administration of Traditional Chinese Medicine [201817]; Hunan key Laboratory Project of Children's Emergency Medicine [2018TP1028]

机构署名：

本校为通讯机构

院系归属：

中西医结合学院

摘要：

Background: The interaction between leukocytes and vascular endothelial cells is ubiquitous in the occurrence and development of many diseases, especially in the body's defense response. The purpose of the present study was to investigate the effect of cornu bubali (CB) on the adhesion of leukocytes to endothelial cells. Materials and methods: Human leukemic cell line (HL-60) and human umbilical vein endothelial cells (HUVECs) were used to simulate the adhesion effect between cells. After HUVECs were treated with TNF-alpha (15 ng/mL) combined with different dose of CB (15, 30 and 60 mu mol/L) ...

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Effects of Cornu Bubali (CB) on the Adhesion of Leukocyte and Endothelial Cells

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