A Clinical TB Detection Method Based on Molecular Typing Technique with Quality Control.

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成果类型：

期刊论文

作者：

Feng, Tienan;Cheng, Yan;Yu, Suwen;Jiang, Feng;Su, Min*;...

通讯作者：

Su, Min;Chen, Jin

作者机构：

[Feng, Tienan] Shanghai Jiao Tong Univ, Sch Med, Shanghai Tongren Hosp, Hongqiao Int Inst Med, Shanghai 200335, Peoples R China.

[Feng, Tienan] Shanghai Jiao Tong Univ, Sch Med, Clin Res Ctr, Shanghai 200025, Peoples R China.

[Cheng, Yan; Yu, Suwen] Peoples Liberat Army 102 Hosp, Dept Neurol, Changzhou 213003, Jiangsu, Peoples R China.

[Jiang, Feng] Dapuqiao Community Hlth Serv Ctr, Shanghai 200025, Peoples R China.

[Su, Min] Hunan Univ Chinese Tradit Med, Affiliated Hosp 1, Dept Lab, Changsha 410007, Hunan, Peoples R China.

通讯机构：

[Su, Min] H

[Chen, Jin] F

[Chen, Jin] S

Hunan Univ Chinese Tradit Med, Affiliated Hosp 1, Dept Lab, Changsha 410007, Hunan, Peoples R China.

First Peoples Hosp, Dept Lab, Lianyungang 222002, Jiangsu, Peoples R China.

语种：

英文

期刊：

Computational and Mathematical Methods in Medicine

ISSN：

1748-6718

年：

2019

卷：

2019

页码：

9872425

DOI：

10.1155/2019/9872425

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81371775]; Shanghai Municipal Health Bureau [20144y0249]; Medical-Engineering Cross Fund of Shanghai Jiaotong University [YG2017QN70]

机构署名：

本校为通讯机构

摘要：

The gold standard for diagnosing pulmonary Mycobacterium tuberculosis (TB) is the detection of tubercle bacillus in patient sputum samples. However, current methods either require long waiting times to culture the bacteria or have a risk of getting false-positive results due to cross-contamination. In this study, a method to detect tubercle bacillus based on the molecular typing technique is presented. This method can detect genetic units, variable number of tandem repeat (VNTR), which are the characteristic of tuberculosis (TB), and performs q...

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A Clinical TB Detection Method Based on Molecular Typing Technique with Quality Control.

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