期刊论文

中文

中西医结合心脑血管病杂志

1672-1349

2008

6

12

1422-1423

10.3969/j.issn.1672-1349.2008.12.020

湖南省教育厅科研基金项目（No.07C484）； 湖南省教育厅青年科研基金项目（No.05B034）；

本校为第一机构

目的 探讨血府逐瘀汤及其拆方对血管平滑肌细胞丝裂原活化蛋白激酶调节因子ERK2 mRNA表达的影响.方法 采用高脂饲料复制动脉粥样硬化模型,原位杂交法检测主动脉ERK2 mRNA的表达.结果 模型组与空白组比较,模型组阳性颗粒为(150.57±25.90)个显著增高(P

Objective To study the effect of Xuefuzhuyu decoction and its seperating prescription on expression of ERK2 mRNA in atherosclerotic vascular smooth muscle cells. Methods The atherosclerosis model rabbits were prepared by high cholesterol diet. The expression of ERK2 mRNA in aortae was delected by hybridization in situ. Results Compared with the blank group,the expression of ERK2 mRNA was remarkably increased in the model group（P〈0.01）. Compared with the model group,the expression of ERK2 mRNA was decreased in Xuefuzhuyu decoction group and T...