Objective:To observe the outcome of Gugutou Huaisiyu Jiaonang(股骨头坏死愈胶囊,GGTHSYJN)in treatment of ster-oid-induced osteonecrosis of femoral head(SONFH),and to explore its underlying mechanism via multiplex immunohistochemistry(mIHC)technique.Methods:One hundred Sprague-Dawley(SD)rats were randomly assigned into normal control group,model group,low-dose drug treatment group and high-dose drug treatment group.After adaptive feeding for one week,the rats in model group,low-dose drug treatment group and high-dose drug treatment group were sub...
