期刊论文

The structure and wear properties of the nitrogen-doped TiO<inf>2-x</inf>N<inf>x</inf> films on brackets

Cao, B.-C.

中文

功能材料

Gongneng Cailiao/Journal of Functional Materials

1001-9731

2012

43

16

2235-2238

基金项目：教育部春晖计划资助项目（Z2008-1-62007） 中央高校基本科研业务费专项资金资助项目（1zujbky-2010-83） 甘肃省国际科技合作基金资助项目（090WCGA903）

本校为其他机构

目的探索miR-199a,HIF-1α在银屑病中的表达及其对表皮细胞增殖的影响。方法首先检测了27例寻常性银屑病患者皮损区和19例健康志愿者皮肤的miR-199a,HIF-1α的表达差异,分析二者之间的相关性;然后在HaCaT细胞中转染miR-199a mimics,用Western blot检测HIF-1α的蛋白表达水平;用双荧光素酶报告基因实验验证miR-199a与HIF-1α的靶向结合关系;最后用MTT法检测miR-199a,HIF-1α对HaCaT细胞增殖的影响。结果银屑病组织中miR-199a的表达下调,HIF-1α的表达上调,且两者存在负相关性;在HaCaT细胞中转染miR-199a mimics可下调HIF-1α的表达;HIF-1α可回复miR-199a对HaCaT细胞增殖的抑制作用。结论 miR-19...

To evaluate the biologic wear properties of the nitrogen-doped TiO2-xNx films on brackets. To produce the nitrogen-doped TiO2-xNx films on the surfaces of stainless steel metal brackets by the method of radio frequency magnetron sputtering. The microstructure and the biologic wear properties of the nitrogen-doped TiO2-xNx films were observed by scanning electron microscopy, X-ray diffraction and type UMT-2MT friction-abrasion testing machine. Results: showed that the microstructure of the nitrogen-doped TiO2-xNx films is sharp titanium mineral, nanometer level and uniformly dense structure;the...