Objective To establish a stable method for determination of total tannins in Jiuxiang Zhixie Tablets. Methods The casein method was used to determine the content of total tannins of Jiuxiang Zhixie Tablets. The conditions of determination is: Supersonic withdraws 30 min by water, used casein 800 mg, coloration in 29% the Na2CO3 30 min. Results The linearity range was 1.0—10.0 μg/mL, r = 0.999 5. The average recovery was 96.58% with RSD of 0.615% (n = 6). Conclusion The method is reliable and could be used to...