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A novel colorimetric assay for sensitive detection of kanamycin based on the aptamer-regulated peroxidase-mimicking activity of Co3O4 nanoparticles

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成果类型:
期刊论文
作者:
Zhou, Xuan;Li, Jiaxin;Hu, Yuda;Wu, Yaohui;Wang, Yonghong;...
通讯作者:
Wang, YH;Ning, G
作者机构:
[Wu, Yaohui; Li, Jiaxin; Hu, Yuda; Wang, Yonghong; Zhou, Xuan] Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol, Int Cooperat Base Sci & Technol Innovat Forest Res, Changsha 410004, Peoples R China.
[Ning, Ge; Ning, G] Hunan Univ Chinese Med, Int Educ Inst, Changsha 410208, Peoples R China.
通讯机构:
[Wang, YH ] C
[Ning, G ] H
Cent South Univ Forestry & Technol, Hunan Prov Key Lab Forestry Biotechnol, Int Cooperat Base Sci & Technol Innovat Forest Res, Changsha 410004, Peoples R China.
Hunan Univ Chinese Med, Int Educ Inst, Changsha 410208, Peoples R China.
语种:
英文
期刊:
Analytical Methods
ISSN:
1759-9660
年:
2023
卷:
15
期:
20
页码:
2441-2447
基金类别:
Hunan Provincial Natural Science Foundation of China [2021JJ31138]; Scientific Research Fund of Hunan Provincial Education Department [20A520]; Training Program for Excellent Young Innovators of Changsha [kq2106053]
机构署名:
本校为通讯机构
院系归属:
国际教育学院
摘要:
Kanamycin is used widely in livestock farming due to its antimicrobial properties and low cost, but has led to antibiotic residues in food, which can damage human health. Therefore, there is an urgent need for convenient technology that can be used to detect kanamycin rapidly. We found that Co(3)O(4) nanoparticles (NPs) possessed peroxidase-like activity that catalyzed the oxidation of 3,3',5,5'-tetramethylbenzidine to change color. Interestingly, a target-specific aptamer could regulate the catalytic activity of Co(3)O(4) NPs and inhibit this ...

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