Alteration of brain structure with long-term abstinence of methamphetamine by voxel-based morphometry

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成果类型：

期刊论文

作者：

Zhang, Zhixue;He, Lei;Huang, Shucai;Fan, Lidan;Li, Yining;...

通讯作者：

Liu, Jun;Yang, R

作者机构：

[Li, Yining; Yang, Ru; Liu, Jun; Zhang, Zhixue; Yang, R; He, Lei; Fan, Lidan] Cent South Univ, Second Xiangya Hosp, Dept Radiol, Changsha, Hunan, Peoples R China.

[Li, Ping; Zhang, Zhixue] Hunan Univ Chinese Med, Fist Hosp, Dept Radiol, Changsha, Hunan, Peoples R China.

[Huang, Shucai] Fourth Peoples Hosp Wuhu, Dept Psychiat, Wuhu, Peoples R China.

[Zhang, Jun] Hunan Judicial Police Acad, Changsha, Hunan, Peoples R China.

通讯机构：

[Liu, J; Yang, R ] C

Cent South Univ, Second Xiangya Hosp, Dept Radiol, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

addiction;gray matter volume;long-term abstinence;methamphetamine;voxel-based morphometry

期刊：

FRONTIERS IN PSYCHIATRY

ISSN：

1664-0640

年：

2019

卷：

页码：

722

DOI：

10.3389/fpsyt.2018.00722

基金类别：

National Natural Science Foundation of China, Grant Number: 81671671. Natural Science Foundation of Hunan Province, China, Grant Number: 2015JJ4081. The National Key Research and Development Program of China (Grant number: 2016YFC0800908).

机构署名：

本校为其他机构

摘要：

Background: A large portion of previous studies that have demonstrated brain gray matter reduction in individuals who use methamphetamine (MA) have focused on short-term abstinence, but few studies have focused on the effects of long-term abstinence of methamphetamine on brain structures. Materials and Methods: Our study includes 40 healthy controls and 44 abstinent methamphetamine-dependent (AMD) subjects who have abstained for at least 14 months. For every AMD subject, the age when they first used MA, the total time of MA use, the frequency o...

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Alteration of brain structure with long-term abstinence of methamphetamine by voxel-based morphometry

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