期刊论文

中文

中国中医药信息杂志

1005-5304

2002

9

4

23-24

10.3969/j.issn.1005-5304.2002.04.009

湖南省自然科学基金课题（№:99JJY20037）；

本校为第一机构

目的:探讨七味白术散对HRV感染乳鼠的NK、IFN-γ、IL-4的影响.方法:将乳鼠随机分成4组,正常对照组常规饲养,其余3组制成HRV感染模型,并分别灌服生理盐水、七味白术散、病毒唑,连续7d.采用放射免疫法观察NK细胞活性,ELISA法观察IFN-γ、IL-4含量的变化情况.结果:七味白术散组的NK细胞活性、IFN-γ、IL-4值高于HRV乳鼠组,两组比较有统计学意义(P＜0.01),与病毒唑组组间比较无统计学意义(P＞0.05).结论:七味白术散能提高HRV感染乳鼠NK活性,增强IFN-γ、IL-4的表达.

Objective:To study the effects of Qiweibaizhu Powder on NK, IFN-γand IL-4 of suckling mice infected with Human Rotavirus(HRV). Methods:Suckling mice were randomly divided into 4 groups, the normal control group bred as normal, the other three groups were made as the model of HRV infection. The normal control group was treated with NS, and the other experimented groups differently treated with Qiweibaizhu Powder, Ribavirin for 7 days. To observe the changes of IFN-γ, IL-4 by ELISA assay and the activity of NK by radioimmunoassay. Results:The s...