版权说明 操作指南
首页 > 成果 > 详情

Novel Insight into the Role of Src Family Kinases in Hepatocellular Carcinoma and Therapeutic Potential

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Yunlong Zhao;Letian Xie;Binwei Liu;Yulin Deng;Pengfei Li;...
通讯作者:
Chun Yi
作者机构:
[Yunlong Zhao; Letian Xie; Binwei Liu; Yulin Deng; Pengfei Li; Yuqing Dai; Jiao Liu; Chun Yi] Department of Pathology, Medical School, Hunan University of Chinese Medicine, Changsha, China
通讯机构:
[Chun Yi] D
Department of Pathology, Medical School, Hunan University of Chinese Medicine, Changsha, China
语种:
英文
期刊:
Biochemical and Biophysical Research Communications
ISSN:
0006-291X
年:
2025
页码:
151970
基金类别:
Fundings This work was supported by the Natural Science Foundation of Hunan Province (No. 2025JJ90042), the Key Project of Academician Workstation Guidance Project (No.22YS002), the Undergraduate Research and Innovation Fund Project of Hunan University of Chinese Medicine(NO.2023BKS051, NO.2024BKS089).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Hepatocellular carcinoma remains a highly aggressive malignancy, with the 5-year survival rate for advanced-stage patients persisting below 20% despite progress in targeted therapies and immunotherapy. This clinical reality underscores the critical need for identifying novel therapeutic targets. Src family kinases (SFKs), critical regulators of cellular metabolism, coordinate regenerative repair through STAT3/ERK signaling in normal hepatic regeneration and preserve cellular polarity via FAK-mediated mechanisms following hepatic injury. Growing evidence suggests that dysregulation of SFKs expr...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com